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Signs can vary depending upon the dose and product to which the dog was exposed. Ibuprofen poisoning may cause many different signs because several organ systems can be affected. What are the clinical signs of ibuprofen poisoning? Dogs that are already taking steroids or another NSAID also have a higher risk of developing signs including gastrointestinal ulceration.

Other current medical conditions such as kidney disease, or liver disease may increase the risk of poisoning. Puppies and older dogs have a higher risk of being poisoned. Poisoning may occur from a single dose or repeated dosing. This recycling prolongs the poisoning effects. Instead of being removed from the body, ibuprofen is released from the liver and reabsorbed in the intestines repeatedly. When ibuprofen is ingested, it is absorbed quickly into the blood stream. Unfortunately, these chemical processes are also important in maintaining normal gastrointestinal, kidney, liver, and blood clotting functions. Ibuprofen, and other NSAIDs, act by blocking certain chemical processes in the body that cause inflammation. Even small doses can cause adverse effects and poisoning. Unfortunately, ibuprofen poisoning is fairly common in dogs, with Pet Poison Helpline, a 24/7 animal poison control center, receiving over 4000 calls each year for ibuprofen exposures in dogs alone. In some cases, owners may administer ibuprofen to treat their pet’s pain prior to consulting a veterinarian. Poisoning may happen when pets get into the owner’s medications.

What is ibuprofen poisoning?Īlthough relatively safe in humans, ibuprofen and other NSAIDs can be extremely harmful to dogs. Typical uses include the treatment of headaches, pain, colds, flu, and menstrual discomfort. These medications may include opioids, antihistamines, decongestants, and acetaminophen. Ibuprofen may be the only ingredient in a medication or be part of a combination product. Ibuprofen is a popular over-the-counter medication and is also available by prescription. Ibuprofen and other NSAIDs treat inflammation by blocking certain processes in the body. Ibuprofen (brand names: Advil, Motrin, Midol, Nuprin) is a commonly-used nonsteroidal anti-inflammatory drug (NSAID) used to treat fever, pain, and inflammation (swelling) in humans.